儿童骨髓增生异常综合征16例临床分析  

Clinical study on childhood myelodysplastic syndrome

作　　者：陈森[1] 贾万英[1] 李静岩[1] 张美玉[1] 姜丽华[1] 

机构地区：[1]天津市儿童医院,天津300074

出　　处：《中国实用儿科杂志》2008年第4期287-289,共3页Chinese Journal of Practical Pediatrics

摘　　要：目的分析儿童骨髓增生异常综合征(MDS)患者的临床特点及预后。方法根据2000年世界卫生组织(WHO)造血以及淋巴组织肿瘤分类方案中关于MDS的最新分型标准对1980年1月至2005年2月于天津市儿童医院就诊的16例儿童MDS患者进行重新分型,对患儿临床表现、临床转归等情况进行分析,并对部分患儿进行随访以观察患者的临床预后。结果部分患者于短期内迅速转化为急性白血病,绝大多数患者于诊断1年左右死亡,临床预后差。结论儿童MDS患者病程预后与成人患者明显不同,病情进展迅速,临床预后欠佳,应进一步加强对此类患者的临床重视与研究。Objective To analyse the clinical data of childhood myelodysplastic syndrome（MDS）.Methods Sixteen patients with childhood myelodysplastic syndrome（MDS）were reclassified according to the criterion of 2000 WHO project and the clinical data from MDS patients were analyzed.Some of the patients were followed up.Results Most patients were evolved to acute myeloid leukemia very sooner and died within one year after diagnosis.Conclusion Myelodysplastic syndrome（MDS）in children has more aggressive clinical course than adults and should pay more attention to them.

关 键 词：骨髓增生异常综合征 儿童 白血病 

分 类 号：R72[医药卫生—儿科]