腺性膀胱炎的研究进展  

The Advances of Research in Cystitis Glandularis

作　　者：刘先夺[1] 范玉铃[2] 

机构地区：[1]天津市人民医院泌尿外科,天津300121 [2]天津市第一中心医院泌尿外科,天津300101

出　　处：《医学综述》2008年第8期1226-1228,共3页Medical Recapitulate

摘　　要：目前,腺性膀胱炎的病因及生物学意义尚未完全明了,但通过研究发现主要是与感染、结石、梗阻、异物、留置导尿管等慢性刺激长期作用,黏膜上皮增生形成Brunn巢有一定关系,另外与ras等基因蛋白和细胞角蛋白19表达异常和人类乳头状瘤病毒感染有关,且具有癌变倾向。其临床表现无显著的特征,诊断依据病理活组织检查,大部分含有Brunn巢。现有的治疗方法较多,包括手术治疗、药物灌注治疗、放射治疗和生物治疗等,多数采用综合治疗,但去除病因的治疗尤为重要。At present, the etiopathogenisis and biological significance ot cystitis glandularis is unclear to some extent. But some investigations show that cystitis glandularis is related to the long-term and chronical stimulus of infection, calculus, obstruction, foreign object, retention type catheter, and to the Bmnn＇s nests resulting from the mucosa epithelial proliferation. Other studies prove that it is closely connected with the abnormal expression of ras gene-proteinum and cytokeratin-19, and with the infection of human papilloma virus. Cystitis glandularis has a tendency of cancerization. Its clinical manifestations have no prominent characteristics. The diagnosis of cystitis glandularis is based on patho-biopsy and appearance of Brunn＇s nests. The treating methods of cystitis glandularis are various, including the operation, drug infusion, radiotherapy, biotherapy, and etc. Comprehensive treatment is employed in most cases. However, to remove etiopathogenisis is an important treating method.

关 键 词：腺性膀胱炎 Brunn巢 癌变 治疗 

分 类 号：R694.3[医药卫生—泌尿科学]