嗅三针治疗血管性痴呆的随机对照研究  

Clinical Investigation on Electroacupuncture Treatment of Vascular Dementia with "Xiusanzhen"

作　　者：刘智斌[1] 牛文民[1] 杨晓航[1] 牛晓梅[1] 

机构地区：[1]陕西中医学院附属医院,咸阳712083

出　　处：《针刺研究》2008年第2期131-134,共4页Acupuncture Research

基　　金：陕西省社发攻关课题资助项目(No.2007K13-03)

摘　　要：目的：观察嗅三针治疗血管性痴呆的临床疗效，以探索有效的治疗方法。方法：60例血管性痴呆患者随机分为两组。针刺组用嗅三针刺激疗法，并施以电针（疏密波，3．85～6．25Hz，0．8～1.0mA），留针1h，每日1次，连续治疗5d后休息2d为1疗程，共治疗10个疗程；药物组用口服药物疗法（都可喜），每次40mg，每日2次，连服5d后休息2d为1个疗程，共治疗10个疗程。分别于治疗前后进行长谷川痴呆修改量表（HDS）、简易智力状态检查表（MMSE）、社会活动能力调查表（FAO）评分。结果：针刺组显效15例，有效9例，无效6例，总有效率为80．00％；药物组显效12例，有效10例，无效8例，总有效率为73．33%；两组疗效比较差异有显著性意义（P〈0．05）。两组患者治疗前后比较，治疗后HDS、MMSE上升，FAO降低，差异有极显著性意义（P〈0．01）；两组间治疗前后差值比较，针刺组的HDS、MMSE、FAO改变比药物组更明显（P〈0．05）。结论：嗅三针对于血管性痴呆患者具有确切的疗效。Objective To observe the effect of electroacupuncture （EA） in the treatment of vascular dementia（VD） so as to explore an effective therapy for it, Methods Sixty cases of VD were randomly divided into acupuncture group and medication （Duxil, 40 mg/time, 2 times/d for 10 weeks） group, with 30 cases in each group. ＂Xiusanzhen＂ means that two acupuncture needles were penetrated subcutaneously from bilateral Yingxiang （LI 20） to Shangyingxiang （EX-HN 8） respectively, and the 3^rd needle was penetrated from the midpoint between two Yangbai （GB 14） through Yintang （EX-HN 3） to the nasal root, followed by applying EA stimulation to the acupoints, Hasegawa＇s Dementia Scale （HDS）, Mini-mental state examination （MMSE）, and Functional Activities Questionnaire （FAQ） were used for assessment of the VD patient＇s state before and after the treatment. Results After the treatment, the total effective rates of acupuncture and medication groups were 80.00% and 73.33% respectively. The effective rate of acupuncture group was significantly superior to that of medication group （P〈0.05）. Before treatment, scores of HDS, MMSE and FAQ in both groups had no significant differences （P〉0.05） ; after the treatment, the scores of HDS and MMSE increased significantly, and that of FAQ decreased remarkably in both groups （P〈0.01）, and the difference of scores （or absolute value of FAQ） between post-treatment and pre-treatment in EA group was obviously higher than that in medication group （P〈0.05）. Conclusion Acupuncture of ＂Xiusanzhen＂ is effective in the treatment of VD patients.

关 键 词：血管性痴呆 嗅三针 电针 

分 类 号：R246.6[医药卫生—针灸推拿学]