不同方法提取川芎中藁本内酯的研究  

Extracting Z-ligustilide from Chuanxiong by Recurrent Extraction Coupling with Absorption

作　　者：沈少华[1] 孙国金[1] 鲍滢[1] 陈姣[1] 

机构地区：[1]浙江中医药大学生物工程学院,浙江杭州310053

出　　处：《浙江化工》2008年第4期1-3,共3页Zhejiang Chemical Industry

基　　金：浙江中医药管理局资助项目(2004Y006)

摘　　要：采用乙醇提取法、水蒸气蒸馏法和循环提取与吸附耦合法提取川芎中藁本内酯,TLC和HPLC分析研究表明:乙醇提取法得挥发油率较高,油中含杂质最多;水蒸气提取法得油率最低,油中杂质最少;循环提取与吸附耦合法得油率较高而杂质较少,同时乙醇用量小,是较适合于藁本内酯等不稳定油性药物提取分离的方法。Z-ligustilide was extracted from Chuanxiong by the method of Recurrent Extraction Coupling with Absorption（RECA）, Ethanol Extraction（EE）, and Steam Distillation（SD） respectively. TLC and HPLC analysis shows： the yield of EE was higher than that of the others, and the purity of SD is highest, RECA can get higher yield and purity, and with smaller consumption. So RECA may be an effective method for extraction of Z- ligustilide （unstable volatile oils）.

关 键 词：藁本内酯 川芎 提取 

分 类 号：R284.1[医药卫生—中药学]