药物后适应在心肌缺血再灌注损伤中的保护作用  

Protective Effect of Pharmacologic Postconditioning on Myocardial Ischemia-reperfusion Injury

作　　者：张丽娜[1] 吴玉林[1] 

机构地区：[1]中国药科大学药学院生理学教研室,江苏南京210009

出　　处：《药学进展》2008年第4期157-162,共6页Progress in Pharmaceutical Sciences

摘　　要：综述有关药物后适应的研究背景和进展。药物后适应是根据心肌缺血后适应机制,通过模拟心肌缺血后适应方法,研究用药物激发或模拟机体内源性保护物质呈现的保护心脏作用,是保护心脏的新途径之一。Pharmacologic postconditioning is based on the mechanism of ischemic postconditioning by the methods of simulating postconditioning to study the cardioprotective role of drug-inspired or simulated endogenous protective substances. Pharmacologic postconditioning is one of the new ways to protect the heart. In this article, the status and progress in this field were reviewed.

关 键 词：药物后适应 缺血再灌注损伤 心肌梗死 

分 类 号：R96[医药卫生—药理学]