麝香滴眼液的抗炎作用  

Anti-inflammatory effect of Musk Eye Drops

作　　者：曹喜红[1] 秦剑[2] 周远大[1] 

机构地区：[1]重庆医科大学附属第一医院临床药理研究室,重庆400016 [2]重庆市中药研究院,重庆400065

出　　处：《中成药》2008年第4期494-497,共4页Chinese Traditional Patent Medicine

摘　　要：目的:研究麝香滴眼液(麝香、冰片等)的抗炎作用。方法:采用二甲苯致小鼠耳肿胀、巴豆油所致家兔急性结膜炎模型以及家兔角膜手术外伤引起的急性角膜炎模型,观察麝香滴眼液的抗炎作用。结果:麝香滴眼液各剂量组均能抑制小鼠耳肿胀,减轻巴豆油所致的急性结膜炎和手术外伤所致急性角膜炎,麝香滴眼液高、中剂量组与空白对照组比较明显优于空白对照组(P<0.05或P<0.01),麝香滴眼液低剂量组虽优于空白对照组,但无统计学意义(P>0.05)。结论:麝香滴眼液有明显的抗炎作用。AIM ： To investigate the anti-inflammatory effect of Musk Eye Drops （ Moschus, Borneolum Syntheticum,etc. ） METHODS： Anti-inflammatory effects of Musk Eye Drops on acute ceratitis in mice was observed with the models of mouse auricle edema induced by dimethylbenzene and acute conjunctivitis caused by Croton oil, and acute ceratitis resulting from surgical injury. RESULTS： All groups of Musk Eye Drops could significantly inhibit the edema ,decrease the inflammatory of acute conjunctivitis and acute ceratitis. The effect of Musk Eye Drops had statistical significance （P 〈0. 05 or P 〈0. 01 ） in high and moderate groups compared with the model group. The effect of Musk Eye Drops in low dose group was better than that of the model control, but no significiant difference was found between them （P 〉 0.05）. CONCLUSION： Musk Eye Drops has obvious anti-inflammatory effect.

关 键 词：麝香滴眼液 抗炎作用 急性结膜炎 急性角膜炎 

分 类 号：R285.6[医药卫生—中药学]