四类典型全身热疗方法加热效果的理论评估  

Theoretical evaluation on heating efficiency for four typical whole body hyperthermia approaches

作　　者：项士海[1] 刘静[1] 

机构地区：[1]中国科学院理化技术研究所,低温生物与医学课题组,北京100080

出　　处：《北京生物医学工程》2008年第1期48-52,104,共6页Beijing Biomedical Engineering

基　　金：国家自然科学基金(50325622)资助

摘　　要：如何快速有效地提高肿瘤患者体核温度是全身热疗实践中的一个十分重要而困难的课题,但目前对现有的各类全身加热措施尚缺乏明确的认识。本文采用有限元数值计算方法,对接近真实边界条件下的四类典型全身热疗措施进行了理论评估,对比分析了不同加热途径的升温效果,指出了进一步提高加热效率的技术策略。研究结果指出,体内加热方式的加热效果最好,也适合于临床操作,应是今后发展高效全身热疗装备的重点。Efficiently raising patient＇s body core temperature is an extremely important however challenging issues during the practice of a whole body hyperthermia （WBH） therapy. Up to now, there is no clear understanding on the effects of various currently existing WBH approaches yet. In this paper, theoretical evaluations on four typical WBH heating methods with boundary conditions close to reality were performed using finite element method. The heating efficiencies for these WBH approaches were examined and compared. Technical strategies to further improve the WBH heating performances were suggested. Specially, as the simulation indicates, the method of interior heating appears to have the highest efficiency and is also suitable for clinical operation. Therefore, it would be an important way to develop high-quality WBH equipment in the near future.

关 键 词：全身热疗 加热策略 加热效率 理论评估 

分 类 号：R318.04[医药卫生—生物医学工程]