灌肠Ⅰ号的制备和质量控制  

Preparation and quality control of Enema Ⅰ

作　　者：朱明恒[1] 

机构地区：[1]苏州市立医院(本部)药剂科,苏州215002

出　　处：《药学与临床研究》2008年第2期152-154,共3页Pharmaceutical and Clinical Research

摘　　要：目的：制备灌肠Ⅰ号并建立质量控制方法。方法：采用水煎煮法制备灌肠Ⅰ号。通过TLC鉴别红花和蒲公英，以HPLC方法测定红花中羟基红花黄色素A的含量。结果：TLC法可明显鉴别红花、蒲公英。羟基红花黄色素A在29．71～297．1μg·mL^-1范围内线性关系良好（r=0．9998），平均回收率为97．5％（RSD=1．22％，n=5）。结论：灌肠Ⅰ号制备工艺简单，质量控制方法简便、准确、稳定、重现性好。Objective：To prepare Enema Ⅰ and establish a method for quality control. Methods： Enema Ⅰ was decocted by water. The Flos carthami and Herba taraxaci in Enema Ⅰ were identified by TLC. The content of hydroxylsafflower yellow A in Flos carthami was determined by HPLC. Results： The Flos carthami and Herba taraxaci could be identified by TLC, and the linear relation of hydroxysafflower yellow A was fine （r =0. 999 8） at the range of 29.71 ～297.1 μg·mL^-1, with average recovery rate of 97.5% （RSD 1.22% ）. Conclusions： The preparation process of Enema Ⅰ is simple. The method of quality control is accurate and reliable.

关 键 词：灌肠Ⅰ号 羟基红花黄色素A TLC HPLC 质量控制 

分 类 号：R944.1[医药卫生—药剂学] R927.1[医药卫生—药学]