在聚乙二醇-水体系中合成二苯甲酮  

Synthesis of Benzophenone in PEG-H_2O System

作　　者：辛炳炜[1] 

机构地区：[1]德州学院化学系,山东德州253023

出　　处：《化学通报》2008年第4期303-307,共5页Chemistry

基　　金：国家自然基金项目(20571063)资助

摘　　要：在聚乙二醇-水(PEG-H2O)反应介质中,以Pd(OAc)2为催化剂,通过苯甲酰氯和苯硼酸的偶联反应,高产率地合成了二苯甲酮。与其他有机溶剂体系相比,Pd(OAc)2-H2O-PEG体系催化效率高(转换数(TON)可高达2.5×104),同时,反应条件温和,反应时间短,产率高,不需要使用污染环境严重的膦配体,是制备二苯甲酮的理想绿色催化体系。The palladium acetate-catalyzed synthesis of benzophenone in the mixture of water and PEG was described. Compared with the previous methods in organic systems, catalytic efficiency of Pd（OAc）2-H2O-PEG was higher, which TONs （ turnover numbers） were up to 2.5 × 10^4 . Pd（ OAc）2-H2 O-PEG was active, air stable, recyclable, and avoiding the use of expensive and environmentally unfavorable phosphine ligand. So it is a desired green medium of synthesis of benzophenone.

关 键 词：二苯甲酮 苯硼酸 苯甲酰氯 聚乙二醇(PEG) 水 

分 类 号：O625.4[理学—有机化学]