黄精提取物对大强度耐力训练大鼠心肌线粒体抗氧化能力及ATP酶活性影响的实验研究  

Effect of Rhizoma Polygonati Red extract on Myocardial mitochondrion Antioxidant Ability and Activity of ATPase in Hyper-intensity Endurance Trained Rats

作　　者：毛雁[1] 马兰军[1] 吕永安[1] 熊正英[2] 

机构地区：[1]西安建筑科技大学体育系,陕西西安710055 [2]陕西师范大学运动生物学研究所,陕西西安710061

出　　处：《四川中医》2008年第2期15-17,共3页Journal of Sichuan of Traditional Chinese Medicine

摘　　要：目的:探讨黄精提取物对大强度耐力训练大鼠心肌线粒体抗氧化能力以及ATP酶活性的影响,为黄精作为运动补剂的开发提供试验依据。方法:通过建立大强度耐力训练大鼠模型,测定心肌线粒体ATP酶、超氧化物歧化酶(SOD)、过氧化氢酶(CAT)、谷胱甘肽过氧化物酶(GSH-Px)活性以及过氧化氢(H2O2)、脂质过氧化产物丙二醛(MDA)的含量,研究黄精提取物对大强度耐力训练大鼠心肌线粒体的保护作用。结果:黄精提取物可明显提高大鼠心肌线粒体在大强度耐力运动中的能量供给、抗氧化能力,防止心肌线粒体的氧化损伤,保证了运动中心脏的正常生理功能。The purpose of this study is to explore the effect and mechanism of Rhizoma Polygonati Red extract on myocardial mitochondrion antioxidant ability and activity of ATPase in hyper-endurance trained rats, which could be useful on its development and clinical application as a sport supplement. Methods： After establishing the hyper-endurance trained rat model, the contents of ATPase, SOD, CAT, GSH-Px, H2O2 and MDA in myocardial mitochondrion were determined to study the effect of Rhizoma Polygonati Red extract on myocardial mitochondrion. Results： The Rhizoma Polygonati Red extract could significantly improve the energy supplying and antioxidant ability of myocardial mitochondrion of rats during high intensity endurance training, and guarantee the normal function.

关 键 词：黄精提取物 心肌线粒体 运动能力 

分 类 号：R285.5[医药卫生—中药学]