聚(衣康酸-癸二酸)的合成及其降解性能  

Synthesis of Poly(itaconic-co-sebacic anhydrides) and its Degradation Property

作　　者：袁军[1] 邓明进[1] 艾军[1] 沈喜洲[1] 郑启新[2] 

机构地区：[1]武汉工程大学湖北省新型反应器与绿色化学工艺重点实验室,湖北武汉430073 [2]华中科技大学生命科学与技术学院,湖北武汉430073

出　　处：《材料科学与工程学报》2008年第2期200-203,共4页Journal of Materials Science and Engineering

摘　　要：将衣康酸和癸二酸作为原料制备了一类新的聚(衣康酸-癸二酸)P(IA-co-SA)共聚酸酐。通过FT-IR、GPC和TG/DTA等手段对聚合物进行了表征,并对不同单体配比共聚酸酐在磷酸盐缓冲溶液中的降解动力学进行了研究。结果表明,共聚酸酐的降解符合一级反应动力学规律,其降解速率随共聚单体SA的比例的增加而减慢。A new kind of polyanhydrides, poly（itaconic-co-sebacic anhydrides）, was successfully made from itaconic acid and sebacic acid. The products were characterized by thermogravimetry and differential thermoanalysis （TG/DTA）, fourier transform infrared spectroscopy （FTIR） and gel permeation chromatography （GPC）. In vitro degradation of copolymers in phosphate buffer solutions was also investigated. The result shows that the degradation mechanism of the copolymers is first-order reaction, and its degradation velocity decreases with the ratio of sebacic acid increasing.

关 键 词：聚(衣康酸-癸二酸) 聚酸酐 降解动力学 

分 类 号：TQ463[化学工程—制药化工]