原婚家庭高血压家庭聚集性研究  

Study on Familial Aggregation of Hypertension in Origi- nal Families

作　　者：张之玮[1] 刘瑛[1] 张连元[1] 赵晓芬[1] 赵晓曦 董淑云[1] 韩向午[1] 孙乃诚 周洪荣 曾宪敏 

机构地区：[1]华北煤炭医学院,唐山063000 [2]唐山唐家庄矿医院

出　　处：《中国公共卫生学报》1997年第6期345-346,共2页

基　　金：国家自然科学基金

摘　　要：以74例高血压患者为先证者进行了家庭系调查。用3种方法估算了遗传度(h^2)。除组内相关法舒张压h^2为50.40％外,其他方法h^2均>62％。经检验,高血压患者在家系中的发生呈家庭聚集现象。提示在高血压家庭聚集性中,遗传因素比环境因素的作用相对更重要。In order to explore the rektive importance of the genetic and the environmental factors in the hypertension, we made family investigation for 74cases of essential hypertension in the o-riginal families.The results were as follows:We got the heritability of essential hypertension h2 = 76. 4 ± 2.1% by using the data of the second degree relatives. The familial aggregation of hypertension existed in original families. The results of research suggest that the effect of genetic factors is relatively more important than the environmental factors in the familial aggregation of hypertension.

关 键 词：高血压 遗传度 家庭聚集性 

分 类 号：R544.101[医药卫生—心血管疾病]