血清脂联素和抵抗素与2型糖尿病及其大血管病变相关  

Association of serum adiponectin and resistin with type 2 diabetes mellitus and its macrovascular complications

作　　者：赵志刚[1] 张会峰[1] 张春玲 汪艳芳[1] 马书平[1] 袁慧娟[1] 苏永[1] 王遂军[1] 

机构地区：[1]河南省人民医院二内分泌科,郑州450003 [2]河南省财经学院外语系

出　　处：《中华内分泌代谢杂志》2008年第2期190-191,共2页Chinese Journal of Endocrinology and Metabolism

摘　　要：测定2型糖尿病患者血清脂联素和抵抗素水平，发现2型糖尿病组血清脂联素浓度（2．51±1．42）mg／L低于正常对照组（5．26±0．78）mg／L，2型糖尿病大血管病变组为（1．38±0．77）mg／L又低于非大血管病变组（3．66±0．91）mg／L，差异均有统计学意义（均P〈0．01）。2型糖尿病组血清抵抗素浓度（7．07±1．11）μg/L高于正常对照组（6．09±0．47）μg/L，2型糖尿病大血管病变组为（7．96±0．65）μg/L又高于非大血管病变组（6．10±0．43）μg/L，差异均有统计学意义（均P〈0．01）。The concentration of serum adiponectin [ （2.51 ± 1.42） mg/L] was lower in the group of patients with type 2 diabetes mellitus as compared with that in normal control group [ （5.26 ± 0.78） mg/L , P 〈 0.01 ]. The concentration of serum adiponectin was lower in the diabetics with macrovascular complications （MVC） [（1.38 ± 0.77）mg/L] as compared with those without macrovascular complication [ （3.66 ± 0.91） mg/ L]. The concentration of serum resistin was higher in the diabetic group as compared with that in control group [ （7.07 ±1.11 vs 6.09 ±0.47） μg/L, P〈0.01]. It was also higher in patients with MVC [ （7.96 ±0.65） μg/ L] compared with those without MVC [ （6.10 ± 0.43） μg/L, P 〈0.01 ].

关 键 词：脂联素 抵抗素 糖尿病 2型 大血管并发症 

分 类 号：R587.1[医药卫生—内分泌]