抗病毒颗粒体外抑制呼吸道合胞病毒的实验研究  

Experimental Research of Kangbingdu Particles inhibition Respiratory Syncytial Virus in Vitro

作　　者：肖四飞[1] 陈生[1] 曲敬来[1] 高雪[1] 刘晓香[1] 

机构地区：[1]广东省深圳市中医院,深圳518033

出　　处：《中国中医急症》2008年第4期521-522,共2页Journal of Emergency in Traditional Chinese Medicine

基　　金：广东省深圳市科技局资助项目(No.200702021)

摘　　要：目的探讨抗病毒颗粒对呼吸道合胞病毒(RSV)的体外抑制作用。方法采用细胞培养技术,以病毒唑为阳性对照药,观察抗病毒颗粒在人喉癌传代细胞(Hep-2)中对RSV的抑制作用。结果在Hep-2细胞中,抗病毒颗粒CC50为9.05,EC50为0.62,TI为2.085,且对RSV抑制作用存在明显的量-效关系。结论抗病毒颗粒在Hep-2细胞中对RSV有明显抑制作用。Objective： To observe the inhibition role of the Kangbingdu Particles to respiratory syncytial virus （RSV） in vitro. Methods： Used cell culture technology, As a positive control drug ribavirin, observed the inhibition role of the Kangbingdu Particles to RSV in the human larynx passage cells （Hep - 2）. Results： In Hep - 2 cells, the CC50 of the Kangbingdu Particles was 9.05, EC50 was 0.62, TI was 2. 085 and there was an obvious dose - response relationship on inhibiting RSV. Conclusion： Kangbingdu particles can inhibite the RSV in Hep - 2 cells significantly.

关 键 词：呼吸道合胞病毒 抗病毒颗粒 体外抑制实验 

分 类 号：R285.5[医药卫生—中药学]