地塞米松穴位注射与重组人粒细胞集落刺激因子皮下注射升白细胞作用对比研究  被引量:3

Function of contrast to study acupoint injection of Dexamethasone and rhG-CSF hypodermic injection rise white blood cell

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作  者:杨丽[1] 

机构地区:[1]湖南省常德职业技术学院护理系,湖南常德415000

出  处:《中国现代医学杂志》2008年第8期1130-1131,1135,共3页China Journal of Modern Medicine

摘  要:目的探讨地塞米松穴位注射与重组人粒细胞集落刺激因子(rhG-CSF)皮下注射在放疗与化疗患者中升白细胞的作用。方法77例白细胞减少患者随机双盲分为治疗组和对照组,治疗组双足三里穴位注射,对照组rhG-CSF皮下注射,每隔5d复查血常规,了解白细胞变化情况。结果治疗组(地塞米松组)毒副作用小,无合并症;对照组(rhG-CSF)毒副作用大,不良反应重,两者比较差异有显著性(P<0.01)。但两者疗效差异无显著性(P>0.05)。结论地塞米松双足三里穴位注射治疗化疗和放疗引起的Ⅰ~Ⅲ级白细胞减少,毒副作用小,疗效确切,方法简便易行,经济方便,值得推广。[Objective] To explore the effect of the acupoint injection of Dexamethasone and the hypodermic injection of recombinant human granulocyte colony-stimulating factor (rhG-CSF) rise the function of white blood cell in the radiotand chemo-therapy patients. [Methods] 77 examples leucopenia patients were randomly bouble blindness assigned to treatment group and control group , the treatment group was given the acupoint injection of Dexamethasone group at dual Zusanli, while the control group received subcutaneous injection of rhG-CSF, each 5d reexamination Boold-Rout and then the lencocyte count alterations were observed between two group. [Results] The treatment group (Dxm group) is be with less adverse and mergence symptom not fount, the control group (rhG-CSF) is very big for poisonous side effect ,and not good response is most heavily, two grops were compared and appeared remarkable differences (P 〈0.01). But two groups were not found obvious difference in curative efficacy (P 〉0.05). [Conclusion] Acupoint injection of Dexamethasone at dual Zusanli can treat Leucopenia of caused Ⅰ-Ⅲ level by radiot-and chemo-therapy for tumors. With less adverse and toxic effect and definite efficacy, is simple, safe, economic and convenient, So it is worthwhile to be used and spread widly.

关 键 词:地塞米松 足三里 rhG—CSF 白细胞 

分 类 号:R969.4[医药卫生—药理学]

 

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