银黄清咽合剂的制备及质量标准研究  

Preparation and Quality Standard of Yinhuangqingyan Mixture

作　　者：邹慧龙[1] 方垒[1] 梁晓美[1] 刘晓霞[1] 

机构地区：[1]浙江省丽水市人民医院,浙江丽水323000

出　　处：《中国药业》2008年第9期40-41,共2页China Pharmaceuticals

摘　　要：目的制备银黄清咽合剂并建立其质量控制方法。方法根据处方制备银黄清咽合剂,采用薄层色谱法对处方中的金银花进行定性鉴别,采用高效液相色谱法测定绿原酸的含量。结果薄层色谱鉴别方法专属性强;绿原酸进样量在0.1984～1.9840μg范围内与峰面积线性关系良好,r=0.9997,平均回收率为99.85%,RSD为1.76%。结论该制剂处方合理,质量控制方法准确、可靠、重现性好。Objective To study the preparation methods and quality standard of Yinhuangqingyan Mixture. Methods According to the prescription, Yinhuangqingyan Mixture was prepared. TLC was used for the qualitative identification of flos lonicerae, and the content of chlorogenic acid was determined by HPLC. Results The identification of flos lonicerae by TLC was special. Chlorogenic acid showed a good linear relationship within the range of 0. 198 4- 1. 984 0 μg, r=0.999 7. The average recovery rate was 99.85%, and RSD was 1.76%. Conclusion The prescription of preparation is rational,and the method of quality control is accurate and reliable with a good reproducibility.

关 键 词：银黄清咽合剂 绿原酸 薄层色谱法 高效液相色谱法 

分 类 号：R286.0[医药卫生—中药学] R284.1[医药卫生—中医学]