藜芦醇的合成工艺研究  

Study on Synthesis of Veratryl Alcohol

作　　者：项晓静 沙兰兰[2] 陈新志[2] 

机构地区：[1]巨化集团公司,浙江衢州324004 [2]浙江大学材料与化学工程学院,杭州310027

出　　处：《化工生产与技术》2008年第2期13-15,共3页Chemical Production and Technology

摘　　要：以藜芦醛为主要原料、异丙醇为溶剂,经硼氢化钠还原、溶剂萃取、减压精馏得到产物藜芦醇。较佳的反应条件为n(硼氢化钠):n(藜芦醛)=0.32:1,温度20℃;实验提高了还原效率、减少了硼氢化钠的耗量;精馏后得到高纯度的目标产品(GC纯度大于98%),产品收率达85.2%;产物经GC-MS分析证明结构正确。Veratryl alcohol was synthesized through the reduction of sodium borohydride from veratraldehyde with isopropanol as solvent, followed by solvent extraction and distillation under reduced pressure. Better reaction conditions are: n(sodium borohydride):n(veratraldehyde)=0.32:1, temperature 20 ℃, under which the reduction efficiency is improved and the consumption of sodium borohydride is reduced. The product is highly pure (GC>98%) with an overall yield of 85.2% after rectification. Structure of the product was confirmed by GC-MS.

关 键 词：藜芦醇 藜芦醛 硼氢化钠 还原 

分 类 号：TQ243.4[化学工程—有机化工]