咪达唑仑与吗啡辅助局麻膝关节镜手术的对比研究  

Local anesthesia arthroscopy procedures of knee joint accompanied by midazolam and morphine—a contrast study

作　　者：李志超[1] 刘玉杰[1] 李众利[1] 王志刚[1] 蔡谞[1] 李光辉[1] 朱娟丽[1] 

机构地区：[1]解放军总医院骨科医院,北京100853

出　　处：《军医进修学院学报》2008年第2期142-143,共2页Academic Journal of Pla Postgraduate Medical School

摘　　要：目的:研究膝关节腔内联合应用利多卡因与吗啡,同时术前静脉应用咪达唑仑在局麻下关节镜手术中的镇痛效果。方法:采用随机双盲对照的试验方法,将105例膝关节镜手术患者分为3组:利多卡因组(A组)、利多卡因+咪达唑仑组(B组)、利多卡因+咪达唑仑+吗啡组(C组),采用视觉模拟评分(VAS评分)对患者术中的镇痛效果进行评估。结果:B组与C组的VAS评分明显优于A组,其差异有统计学意义;C组的VAS评分低于B组,但其差异无统计学意义。结论:局麻下关节镜手术使用咪达唑仑可以加强利多卡因的镇痛效果,术中有利于肌肉松弛,减轻患者恐惧心理,利于手术操作。Objective：To investigate the analgesic effects of inn＇a-articular lidocaine and morphine accompanied with preoperative intravenous midazolam following local anesthesia arthmscopy procedures of knee .joint. Methods： In this double-blind control study, 105 patients were ready to undergo local anesthesia arthmscopy procedures of knee joint. They were randomized in three equal number groups ： A （Lidocaine）, B （ Lidocaine and Midazolam） and C （ Lidocaine, Midazolam and Morphine）. Pain levels during the operation were measured by the Visual Analog Scale（VAS）. Results： The VAS scores of Group B and C were significantly lower than that of Group A （ P 〈 0.05）. The scores of Group C was a little lower than that of Group B. However, there was no statistical significance between them（ P 〉 0.05 ）. Conclusion： Preoperative intravenous midazolam can enhance the anal- zesic effects of lidocaine. It is also helnful for the natiants to keep relaxed and makes the operation ensier.

关 键 词：咪达唑仑 吗啡 关节镜 

分 类 号：R684[医药卫生—骨科学]