尿中Bpn与冠状动脉粥样硬化的相关性研究  

Relationship between urinary biopyrrin and coronary atherosclerosis

作　　者：佟凤芝[1] 王婷婷[1] 刘明开[1] 

机构地区：[1]大连大学附属新华医院检验科,辽宁116021

出　　处：《国际检验医学杂志》2008年第4期303-304,共2页International Journal of Laboratory Medicine

摘　　要：目的探讨尿中biopyrrin与冠状动脉粥样硬化的相关性。方法选择2006年4月- 2007年4月220例经冠状动脉造影检查的住院患者,分为1支病变组(A组)80例,2支病变组(B组) 75例,3支病变组(C组)65例,同时选择性别年龄相同的冠状动脉健康组(对照组)80例,对所有患者进行检测。结果健康对照组与A、B、C组尿中biopyrrin差异有统计学意义(P<0.05),各组间差异亦有统计学意义(P<0.05)。结论biopyrrin与冠状动脉受累范围呈正相关,并且随着冠状动脉病变支数的增多biopyrrin明显提高。Objective To study the relationship between urinary biopyrrin level and the degree of coronary atherosclerosis. Methods 220 inpatients with coronary artery disease,which were identified by coronary angiography within 1 year （from April 2006 to April 2007）, and 80 healthy examinees （healthy group） were enrolled in the study. The 220 inpatients were divided into three groups according to the involved number and extent of coronary arteries： 1 vessel group （group A,n=80）, 2 vessel group （group B,n = 75） and 3 vessel group （group C, n = 65）. Enzyme linked immunosorbent assay （ELISA） was applied to detecting urinary biopyrrin level for all subjects. Results Compared with that of healthy control group, the urinary biopyrrin in group A, B and C was much higher （P〈0.05）. There were statistical difference of urinary biopyrrin level among the different groups r （P〈0.05）. Conclusion Biopyrrin is significantly associated with the involved number and extent of coronary arteries.

关 键 词：胆红素 氧化物 尿 冠状动脉硬化 

分 类 号：R543[医药卫生—心血管疾病]