儿科病房产超广谱β-内酰胺酶菌的检测  

Survey of bacteria producing extended-spectrum beta-lactamase in pediatrics

作　　者：李瑞珍[1] 马新瑜[1] 何文军[1] 刘先洲[2] 唐芳[1] 陈莎[1] 罗德涓[1] 

机构地区：[1]湖北省武汉市妇女儿童医疗保健中心内科,430016 [2]武汉大学医学院微生物教研室

出　　处：《中国妇幼保健》2007年第8期1064-1065,共2页Maternal and Child Health Care of China

摘　　要：目的:调查儿科病房产超广谱β-内酰胺酶(extended-spectrum beta-lactam ases,ESBLs)菌的感染和耐药状况。方法:用纸片初筛试验和表型确证试验检测ESBLs,用K-B纸片扩散法对抗菌药物进行敏感试验。结果:大肠埃希菌和克雷伯菌是产ESBLs的两种主要革兰氏阴性杆菌。产ESBLs菌的耐药率与不产ESBLs菌相比差异有显著性。结论:儿科病房产ES-BLs菌所导致的感染已不容忽视;产ESBLs菌对大多数抗生素耐药。Objective ： To investigate the infection and drug resistance of extended - spectrum beta - lactamases （ESBLs） - producing bacteria in pediatrics. Methods： ESBLs were detected by two kinds of methods. The drug - sensitive test of ESBLs - producing strains was done according to K - B method. Results： Escherichia coli and Klebsiella were two main kinds of ESBLs - producing bacteria. There were significant differences between the resistance rates of ESBLs - producing strains and no ESBLs - producing strains. Conclusion： The infections of ESBLs - producing strains are serious in pediatrics. The resistant rates of ESBLs - producing strains to most antibiotics are high.

关 键 词：超广谱Β-内酰胺酶 耐药性 儿科 

分 类 号：R722[医药卫生—儿科]