急性脑梗死毒损脑络机制探析  

Mechanism of brain collateral lesion by toxin of acute cerebral infarction

作　　者：刘超[1] 张允岭[1] 陶冶[1] 陈志刚[1] 郭蓉娟[1] 

机构地区：[1]北京中医药大学东方医院,北京100078

出　　处：《北京中医药大学学报》2008年第4期221-224,共4页Journal of Beijing University of Traditional Chinese Medicine

基　　金：国家重点基础研究发展计划(973计划)项目(No.2006CB504805);教育部新世纪优秀人才支持计划(No.NCET-05-0139)

摘　　要：急性脑梗死毒损脑络机制是对中风病传统病因病机认识的提升。毒有外内之别,毒损脑络之毒多为内毒,且内毒为病,易损络脉,并可进一步败坏脏腑,使病情加重恶化,难治难愈。络脉为结构与功能的统一体,着眼于气络与血络,则可从功能与结构上对络脉进行整体概括并开展相关生物学基础研究。立足于络脉功能障碍与结构损伤,围绕邪蕴成毒,毒成络损来论述病气络、病血络的动态病理过程,并结合急性脑梗死缺血级联反应,试从急性脑梗死病理损害过程阐述毒损脑络机制的科学内涵。The analysis on the mechanism of brain collateral lesion by toxin of acute cerebral infarction （ACI） improves the recognition of traditional cause and pathogenesis of apoplexy. Toxin can be divided into internal toxin and external toxin, and the toxin that damages the brain collaterals is the internal toxin, which usually injures the collaterals when it induces diseases. It will further damage viscera and bowels and finally lead to the condition of aggravation and deterioration in many difficult and urgent diseases. Collaterals unify the function and structure of the body. Through studying the function and structure of collaterals, classifying qi collaterals and blood collaterals, we can grasp the holo-character of collaterals and conduct biology research work on collaterals. Here the pathological dynamic process of disordered qi-collaterals and blood-collaterals was expounded on the base of malfunction and structure destroy of collaterals and according to the process of pathogenic factor turned into toxin and collaterals damaged by toxin. The scientific connotation was explained on the base of the pathological process of acute cerebral infarction combined with the ischemia cascade reaction of acute cerebral infarction.

关 键 词：脑梗死 毒损脑络 病因病机 

分 类 号：R228[医药卫生—中医基础理论]