The task dependent interaction of the deactivation regions  

作　　者：ZHANG Ye FENG ShiGang FENG HongBo DONG Feng TANG YiYuan 

机构地区：[1]Institute of Neuroinformatics and Laboratory for Body and Mind, Dalian University of Technology, Dalian 116024, China [2]Key Lab of Mental Health, Chinese academy of Sciences, Beijing 100101, China

出　　处：《Chinese Science Bulletin》2008年第10期1527-1532,共6页

基　　金：the National Natural Science Foundation of China (Grant Nos. 60472017 and 30670699);Ministry of Education of China (Grant No. NCET-06-0277);the Research Fund for the Doctoral Program of Higher Educa-tion (RFDP) (Grant No. 021010)

摘　　要：Although deactivation has been found frequently in former functional brain imaging researches, only recently has it become a focus of systematic study because of its not well understood physiological mechanism. However, most of the researches concentrated on the brain areas that would present de-activation, and, to our knowledge, the deactivation connectivity between these brain areas during the cognitive tasks has rarely been reported in literature. In this work, using the functional connectivity method WICA (within-condition interregional covariance analysis), we analyzed the deactivations in two different cognitive tasks――symbol orientation and number comparison. The results revealed deactivations in the posterior cingulate, precuneus, anterior cingulate and prefrontal cortex in both tasks. However, the interaction between the deactivated regions shows many differences. Our result further indicates that the potential implication of special deactivation connectivity may be related to the different task or attention resource. Further research is needed to clarify the exact reason.Although deactivation has been found frequently in former functional brain imaging researches, only recently has it become a focus of systematic study because of its not well understood physiological mechanism. However, most of the researches concentrated on the brain areas that would present deactivation, and, to our knowledge, the deactivation connectivity between these brain areas during the cognitive tasks has rarely been reported in literature. In this work, using the functional connectivity method WlCA （within-condition interregional covariance analysis）, we analyzed the deactivations in two different cognitive tasks symbol orientation and number comparison. The results revealed deactivations in the posterior cingulate, precuneus, anterior cingulate and prefrontal cortex in both tasks. However, the interaction between the deactivated regions shows many differences. Our result further indicates that the potential implication of special deactivation connectivity may be related to the different task or attention resource. Further research is needed to clarify the exact reason.

关 键 词：失活作用 FMRI WlCA 生理学 

分 类 号：Q1[生物学—普通生物学]