不同光照时间对BALB/c裸小鼠生长发育及繁殖影响的比较研究  

A Comparative Study on Effects of Three Different Illuminations Durations on Growth,Development and Reproduction of BALB/c Nude Mice

作　　者：李志东[1] 王晖[1] 欧阳轶强[1] 练有文[1] 陈荣花[1] 

机构地区：[1]广东医学院实验动物中心,湛江524023

出　　处：《实验动物科学》2008年第2期13-15,共3页Laboratory Animal Science

基　　金：广东省科技计划项目(编号:2004B60301011)

摘　　要：目的比较不同光照时间对BALB/c裸小鼠的影响。方法观察裸小鼠出生后在不同光照时间里的生长情况;记录雌鼠的交配分娩间隔、生产胎数、产仔数及育成率;测定血液生化指标。结果各组裸小鼠的生长差异不显著(P>0.05);中光照组的平均育成率和离乳裸鼠育成率与长光照组比较差异显著(P<0.05);中光照组的ALT、TB、SUA与长光照组比较差异显著(P<0.05)。结论中光照和短光照适宜BALB/c裸小鼠的生长发育和繁殖。Objective To observe and compare effects and reproduction of BALB/c nude mice. Methods of three different illumination durations on growth, development Newborn BALB/c nude mice were fed under three different illumination durations, and their growth and development were observed. Mating and delivery intervals, delivery frequency, and number born were observed in female BALB/c nude mice, and rate of offspring survival was recorded. Some blood biochemical indexes were determined by LX20 semi-automatic analyzer. Results The differences in growth and development of newborn BALB/c nude mice were not significant among three different illumination durations （ P 〉 0.05）. The average rate of offspring survival in the group of middle illumination duration was significantly higher than that in the group of long illumination duration （ P 〈 0.05）. The differences in ALT, TB and SUA between the group of middle illumination duration and the group of long illumination duration were significant statistically （P 〈 0.05 ）. Conclusion The middle and short illumination durations are more suitable to growth, development and reproduction of BALB/c nude mice than long illumination duration.

关 键 词：光照 BALB/C裸小鼠 血液生化指标 生长发育 

分 类 号：Q95-33[生物学—动物学]