高性能多孔β-TCP陶瓷/明胶复合材料制备研究  

Preparation of High Performance Porous β-Tricalcium Phosphate/Gel Scaffold

作　　者：龚立[1] 季金苟[1] 陈松[1] 周治国[1] 陈际达[1] 徐溢[1] 

机构地区：[1]重庆大学化学化工学院,重庆400044

出　　处：《稀有金属材料与工程》2008年第A01期168-171,共4页Rare Metal Materials and Engineering

基　　金：重庆市自然科学基金(CSTC2006BB4179)

摘　　要：采用Ca(OH)_2/H_3PO_4中和反应,超声分散条件下制备β-TCP粉末原料;通过致孔剂方法制备多孔β-TCP支架,并在β-TCP成型过程中加入K_2HPO_4提高支架强度;将制备的多孔支架与明胶复合,冷冻干燥后与戊二醛交联,得到多孔β-TCP/明胶复合支架。实验表明,加入K_2HPO_4后提高了支架强度,当多孔β-TCP支架孔隙率为49.47%时抗压强度为7.60 MPa。多孔β-TCP支架的孔隙率高、强度高、孔隙大小可控、孔隙连通性好;进一步与明胶复合后,制备的多孔β-TCP/明胶复合材料,符合组织工程结构特征的要求。Pure β-TCP powders were prepared from Ca（OH）2/H3PO4 in the ultrasonic field, The powders were added with K2HPO4 and mixed with porogens as the stearic acid. The porous β-TCP scaffolds were mixed with gelatin and cross-linked with glutaraldehyde. The compressive strength of the porous β-TCP scaffold by the addition of K2HPO4 was increased. The composite of porosity 49.47% has the compressive strength of 7.60 MPa. The pores in the β-TCP scaffolds were homogeneous and interconnected, and the β-TCP/Gel composite scaffold was close to bones in its composition and structures.

关 键 词：Β-TCP 明胶 复合材料 

分 类 号：TB333[一般工业技术—材料科学与工程]