红外激光心肌打孔热损伤的计算研究  

Computation on the Thermal Lesion of Infrared Laser Revascularization*

作　　者：罗乐[1] 吴本科[1] 张霆[1] 宗仁鹤[1] 邓善熙[1] 

机构地区：[1]合肥工业大学理学院,安徽合肥230009

出　　处：《应用激光》2008年第2期164-166,共3页Applied Laser

基　　金：国家自然科学基金项目(编号:39170725);校科研究发展基金项目(编号:031002F)

摘　　要：根据红外激光心肌打孔的机理建立热传导产生热损伤的理论模型,采用有限元算法对打孔时间不同、孔径不同的激光孔道周围心肌组织的温度分布情况进行了计算研究。并根据计算结果对红外激光心肌打孔导致热损伤的规律进行了研究。研究结果表明:随着打孔时间的增大,孔道周围心肌组织热损伤的范围明显增大。而孔径的改变对热损伤的范围没有显著的影响。并且打孔时间控制在0.3s以内时,单纯由热传导所导致的心肌组织实质性热损伤的最大范围在40μm以内。The theoretic model for heat exchange to cause thermal lesion was established according to the principle for infrared laser revascularization in myocardium. The myocardial temperature distribution round laser channel was computed with the help of the computer and the finite element when the aperture and the duration of laser irradiation were different. Then the regularity for infrared laser revascularization to cause myocardial thermal lesion was detailedly studied according to compt, tation. The research document： the area of myocardial thermal lesion was expanded obviously when the duration of laser irradiation was extended. The variety of the aperture influenced the area of myocardial thermal lesion feebly. The maximal area of material lesion caused by heat exchange in myocardium round laser channel was less than 0.04mm when the duration of laser irradiation was less than 0.3s.

关 键 词：红外激光 心肌组织 热损伤 理论模型 有限元 计算研究 

分 类 号：TP334.2[自动化与计算机技术—计算机系统结构] Q463[自动化与计算机技术—计算机科学与技术]