无创双水平气道正压通气对慢性阻塞性肺疾病患者生存质量的影响  

Influences of noninvasive bi-level positive airway pressure ventilation on quality of life of patients with chronic obstructive pulmonary disease

作　　者：曾玉兰[1] 杨荣时[1] 

机构地区：[1]华中科技大学同济医学院梨园医院呼吸内科,武汉市430077

出　　处：《实用医学杂志》2008年第8期1327-1329,共3页The Journal of Practical Medicine

摘　　要：目的:探讨使用无创双水平气道正压通气(BiPAP)对慢性阻塞性肺疾病患者生存质量的影响。方法:52例慢性阻塞性肺疾病患者分成治疗组(n=26)和对照组(n=26)。对照组给予常规氧疗,同时进行呼吸功能锻炼;治疗组给予BiPAP呼吸机辅助通气,每日使用3～4次,每次使用2h。两组均同时使用支气管扩张剂等药物和营养治疗,4周为1个疗程。利用生存质量评分标准分别在治疗前、治疗后2周、治疗后4周对两组患者进行生存质量评估。结果:治疗组治疗后其生存质量总均分(TMS)及日常生活能力(F1S)、社会活动情况(F2S)、抑郁心理状态(F3S)、焦虑心理症状(F4S)评分较治疗前降低,差异有显著性(P<0.05)。而对照组差异无显著意义(P>0.05)。结论:使用BiPAP可以减轻慢性阻塞性肺疾病患者的气流阻塞,改善患者的呼吸功能,减轻症状,增加活动范围,从而提高生存质量。Objective To explore the influences of noninvasive bi-level positive airway pressure （BiPAP） ventilation on quality of life （QOL） in patients with chronic obstructive pulmonary disease （COPD）. Methods 52 patients with COPD were divided to receive 2-hour BiPAP ventilation thrice or four times daily （n = 26） or conventional oxygen therapy with respiratory exercises as control （n = 26）. Both groups also received bronchodilators and nutrition therapy. Four weeks was a cycle. The QOL of the patients was assessed using the QOL scale pretherapeutically and 2 and 4 weeks after treatment. Results In the BiPAP ventilation group, the scores for total medial score （TMS） of QOL, ability of daily living （FIS）, capability of social activity （F2S） , state of depression （F3S）, and symptom of anxiety （F4S）were declined markedly as compared with the baseline （P 〈 0.05）. However, There were no significant differences in those in the control group （P〉0.05）. Conclusion Noninvasive BiPAP ventilation for COPD may relieve obstruction to the airflow, improve respiratory function, and alleviate symptoms, leading to the improvement of QOL.

关 键 词：肺疾病 慢性阻塞性 双水平气道正压通气 生存质量 

分 类 号：R563.9[医药卫生—呼吸系统]