茶碱类药治疗哮喘作用评价  

Therapeutic Effect of Theophylline for Asthma

作　　者：贺金莲[1] 

机构地区：[1]湖南娄底市中心医院,娄底市417000

出　　处：《中国医院用药评价与分析》2008年第3期176-177,共2页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:分析茶碱在临床治疗哮喘中的作用及注意事项,评价其疗效供临床参考。方法:查阅有关资料报道,近来研究发现小剂量的茶碱具有抗炎和免疫调节作用,再次引起了广大医务工作者对茶碱在临床应用的极大兴趣。结果与结论:合理的药物治疗可以控制哮喘,茶碱类药物的药理作用极为广泛,除舒张支气管平滑肌外,尚有兴奋呼吸中枢,增加膈肌收缩力,强心利尿和降低肺血管张力及减少肺血管渗出的作用。所以,至今在有些国家和地区仍将茶碱作一线平喘药物用于临床。OBJECTIVE： To discuss the therapeutic effect of theophylline in clinical treatment of asthma and the announcements, and to evaluate its efficacy for clinical reference. METHODS： It has been reported in recent literature that small dose of theophylline＇s has the action of anti-inflammatory and immunoloregulation, which once again aroused medical workers＇ widespread interest on its clinical application. RESULTS ＆ CONCLUSION： Asthma can be treated with rational drug treatment. Due to the extensive pharmacological actions such as relaxing tracheal smooth muscle, exciting respiratory center, increasing myotility of diaphragmatic muscle, cardiocinetic and diuretic action, lowering pulmonary angiotasis, reducing pulmonary vascular exudation, theophylline are still the first line anti-asthmatic drugs in the clinic in some countries.

关 键 词：茶碱 控制哮喘 平喘药 

分 类 号：R974.3[医药卫生—药品]