酚氧化酶及其酶原的研究进展(Ⅱ)——免疫学特性、细胞定位及其功能  

Progress in phenoloxidase & its prophenoloxidase (Ⅱ)——immunological character,cellular localization and its function

作　　者：庞秋香[1] 庞书香[2] 赵博生[1] 

机构地区：[1]山东理工大学生命科学院,山东淄博255049 [2]济宁职业技术学院生化系,山东济宁272037

出　　处：《现代生物医学进展》2008年第7期1385-1388,共4页Progress in Modern Biomedicine

基　　金：国家自然科学基金(No 39770091)

摘　　要：酚氧化酶(Phenoloxidase,PO)又称为酪氨酸酶(tyrosinase,EC1.14.18.1),是一种含铜的酶,能够催化单酚羟化成二酚(如多巴),并把二酚氧化成醌;醌在非酶促条件下形成最终的反应产物黑色素。PO在脊椎动物和无脊椎动物中都广泛存在,而且被认为是一种参与免疫的重要因子。本文就酚氧化酶及其酶原的免疫学特性、细胞定位及其功能研究进展进行综述。Phenoloxidase （PO） is also called tyrosinase （EC1.14,18.1）. It is an enzyme containing copper and exists widely in the vertebrates and invertebrates and is considered as an important factor participating in the immune responses. It catalyzes the monohydric phenol to hydroxylate into diphenol （such as dopa） which is oxidized into quinone which is formed into the final reaction product melanin. This paper reviewed the immunological character, cellular localization and fimction and research advances of PO.

关 键 词：酚氧化酶 酚氧化酶原 免疫学特性 细胞定位 功能 

分 类 号：Q-1[生物学]