太空及微重力环境对免疫系统影响的研究进展  

The Change of Immunity Under the Space and Microgravity Environment

作　　者：张华[1] 贾秀志[1] 张凤蕴[1] 

机构地区：[1]哈尔滨医科大学免疫学教研室,150081

出　　处：《国际免疫学杂志》2008年第1期77-79,F0003,共4页International Journal of Immunology

基　　金：国家“863”科技项目资助（2003AA744052）;黑龙江省教育厅科技研究项目（10551137）

摘　　要：空间飞行对机体的免疫系统的影响很大，胸腺及脾脏有萎缩性变化，各种免疫细胞的功能都有所降低。其影响的机制非常复杂，主要涉及两方面，一是空间环境造成机体的神经内分泌机能发生改变，从而影响免疫功能；二是空间失重环境导致免疫细胞的结构和功能发生变化。航天中的其他因素，如应激、噪声、辐射等也会对改变机体的免疫功能。Results of studies from several laboratories have indicated that during space flight immunity is greatly altered, such as atrophied thymus and spleen, depressed lymphocytes function. The mechanism of space influence is very complex and mainly involves two aspects：one is the change of neuroendocrine system, the other is the stucture and function alteration of immunocytes. Simultaneously, stress, radiation, noise, stress and many other yet undetermined factors in space flight maybe the causes of alteration of the immune system.

关 键 词：空间飞行 微重力 免疫 

分 类 号：R85[医药卫生—航空、航天与航海医学]