细胞因子抗瘢痕的研究进展  

Research progress in anti-scar effect of cytokines

作　　者：张刚[1] 谭军[2] 李高峰[2] 

机构地区：[1]南华大学医学院,湖南衡阳421001 [2]湖南省人民医院整形美容科,湖南长沙410005

出　　处：《现代生物医学进展》2008年第6期1175-1177,共3页Progress in Modern Biomedicine

摘　　要：瘢痕是创伤修复的必然结果影响,瘢痕的产生,发展的因素很多,虽然国内外学者在病理性瘢痕领域研究取得了一些进展,但其确切的发病机制仍未完全清楚,目前对治疗瘢痕的研究主要集中在生化,细胞水平,对分子机制和基因水平的研究还在不断的深入,人们对细胞因子在瘢痕形成方面起了关键的调节作用这一观点已逐步形成共识,并将细胞因子引入瘢痕的治疗中。常见的细胞因子在抗瘢痕中的应用也将成为可能。本文主要介绍了常见细胞因子的在创面修复中的生物学特征及抗瘢痕的研究情况。Scar is the inevitable result of wound healing. There are a number of factors which cause the generation of scars, Although there has been some progress in the field of the disease rational scar from the research of domestic and foreign scholars, its precise mechanism has not yet fully been elucidated. The present study on the treatment of scar mainly focuses on biochemistry, cell level, the molecular mechanisms and genetic research and these aspects are growing in the level of depth. That the cytoklnes plays a key role in the regulation of the formation of scar has been gradually formed a consensus and the cytokines is introduced into the treatment of scars. Common cytoklnes will become possible in the application of anti-scar. This article introduces the biological characteristics of a common cytokines in wound repair and the anti-scar research.

关 键 词：细胞因子 瘢痕 研究进展 

分 类 号：R622.9[医药卫生—整形外科]