创伤性休克患者肠道分泌型免疫球蛋白A含量的变化  

Content Change of Intestinal sIgA of Patients with Traumatic Shock

作　　者：石晶[1] 于素云[1] 赵连爽[1] 黄秀霞[1] 范滨[1] 

机构地区：[1]中国医科大学附属第一医院检验科,辽宁省沈阳市110001

出　　处：《中国全科医学》2008年第9期803-804,共2页Chinese General Practice

摘　　要：目的观察创伤性休克患者肠道sIgA含量的变化。方法收集2006年3月—2007年3月中国医科大学附属第一医院重症医学科收治的63例创伤性休克患者的粪便及血清,同时收集同期体检中心的50例健康体检者作为对照。应用放射免疫分析法检测粪便中分泌型免疫球蛋白A(sIgA)含量,应用免疫散射比浊法检测血清中IgA含量。结果创伤性休克患者和对照者肠道内sIgA含量间差别有统计学意义(P<0.05),而血清IgA含量间差别无统计学意义(P>0.05)。结论创伤性休克时肠道内sIgA含量明显下降,并且此下降不依赖于血清IgA水平。Objective To investigate the change in content of intestinal sIgA of patients with traumatic shock. Methods One hundred and twenty - six inpatients with traumatic shock, admitted from March of 2006 to March of 2007 in the critical department of the first affiliated hospital of China Medical University, and one hundred and fifty health checkup peoples were enrolled. The serum IgA and fecal sIgA were examined by immunity rate nephelometry and radioimmunoassay. Results The content of intestinal sIgA of patients with traumatic shock remarkably decreased as compared with that of the controls （ P 〈 0.05 ）, but there was no significant differences in the level of serum IgA between the traumatic shock patients and controls （ P 〉 0. 05 ）. Conclusion The content of intestinal sIgA remarkably decreased in patients with traumatic shock, which was not dependent on the level of serum IgA.

关 键 词：休克 创伤 免疫球蛋白A 血清 粪便 

分 类 号：R446.6[医药卫生—诊断学]