南极海单胞菌BSw10005发酵液化学成分的研究  

Studies on the chemical constituents of the fermentation broth from antarctic Marinomonas sp.BSw10005 strain

作　　者：高海锋[1] 张道敬[1] 魏鸿刚[1] 沈国敏[1] 陈波[2] 李元广[1] 

机构地区：[1]华东理工大学生物反应器工程国家重点实验室,上海200237 [2]中国极地研究中心,上海200136

出　　处：《中国海洋药物》2008年第2期14-17,共4页Chinese Journal of Marine Drugs

基　　金：上海市重点学科建设项目资助(B505)

摘　　要：目的研究海单胞菌BSw10005发酵液中的化学成分。方法采用硅胶柱色谱法和Sephadex LH-20分离纯化,通过波谱法进行结构鉴定。结果从发酵液中分离得到6个化合物,鉴定其结构为对羟基苯甲醛(Ⅰ)、苯甲酸(Ⅱ)、吲哚-3-乙酸(Ⅲ)、吲哚-3-甲醛(Ⅳ)、吡咯-2-甲酸(Ⅴ)、环(脯氨酸-甘氨酸)二肽(Ⅵ)。结论以上各化合物均为首次从海单胞菌属中分离得到。Objective To study the chemical constituents from Marinornonas sp. BSw10005. Methods Six compounds were isolated by silica gel column chromatography and Sephadex LH-20, and their structures were elucidated by means of spectral analysis. Results Their structures were identified as p-hydroxybenaldehyde （ Ⅰ ）, benzoic acid （ Ⅱ ）, indole-3-acetic acid （ Ⅲ）, 3-indolealdehyde （Ⅳ）, 2-pyrrolecarboxylic acid （ Ⅴ ）, Cyclo （Pro-Gly） （ Ⅵ ）. Conclusion All the compounds were isolated from this genus for the first time.

关 键 词：海单胞菌 化学成分 分离 结构鉴定 

分 类 号：Q939.1[生物学—微生物学]