^103pd放射性支架的三维剂量率分布  

Three-dimensional dose rate table for ^103pd radioactive stent

作　　者：徐志勇[1] 张良安[2] 戴光复[2] 苑淑渝[2] 

机构地区：[1]复旦大学肿瘤医院放疗科,200032上海 [2]中国医学科学院放射医学研究所

出　　处：《中华放射肿瘤学杂志》2008年第3期230-233,共4页Chinese Journal of Radiation Oncology

基　　金：国家自然科学资助项目（30170233）

摘　　要：目的研究^103Pd放射性支架的三维剂量率分布。方法用模拟实验、理论计算和蒙特卡罗代码（MCNP4b）3种方法估算3mm×13mm支架的表面剂量、表面轴向剂量和径向分布，支架活度为2．9×10^6Bq。用MCNP4b计算支架的三维剂量率分布。结果模拟实验和MCNP4b计算的支架表面剂量分别为0．109、0．106Gy，两者差异〈3％。理论计算和MCNP4b计算的轴向剂量一致。3种方法计算的径向剂量也一致。用MCNP4b估算了^103Pd放射性支架三维剂量率分布。结论3种方法估算的^103Pd放射性支架的剂量都比较准确。用MCNP4b计算的支架三维剂量率分布数据可为动物实验和临床应用提供剂量学参考。Objective To investigate three-dimensional dose distribution for ^103pd radioactive stent. Methods The surface dose,the axial dose and radial dose in surface for ^103pd stent （3 mm × 13 mm） were estimated by experimental simulating method, analytic function and MCNP4b code. Three-dimensional dose distribution was calculated by MCNP4b code. Results The surface dose of ^103Pd stent was 0. 109 and 0. 106 Gy estimated by experimental simulating method and MCNP4b code,between which the difference was less than 3%. The axial dose calculated by analytic function and MCNP4b code was well consistent, and so was the radial dose estimated by the three methods. Dose rate table were estimated by MCNP4b code. Conclusions Dose distribution for ^103 Pd stent estimated by the three methods is relatively accurate. Three-dimensional dose table estimated by MCNP4b may be used to calculate dose for ^103pd stent in animal experiment and clinical application.

关 键 词：放射性支架 再狭窄 剂量点核函数 蒙特卡罗代码 

分 类 号：R686[医药卫生—骨科学]