高血压病近日节律变化特征的研究  

Circadian rhythm variation in hypertensive disease

作　　者：关俊文[1] 刘衍宇[2] 江舟[1] 王正荣[1] 

机构地区：[1]四川大学基础与法医学院生物医学工程研究室,四川成都610041 [2]广东医学院第二附属医院,广东湛江524003

出　　处：《西部医学》2008年第3期480-481,484,共3页Medical Journal of West China

摘　　要：目的通过近日节律的分析,了解高血压病血压近日节律各参数变化的特征。方法收集高血压病例共59例,正常对照组74例。分别进行连续24小时血压的监测,每30分钟记录一次。用余弦法分析两组数据的近日节律特征,两组节律参数用t检验进行比较。结果正常对照组、高血压组均存在近日节律,高血压病患者的调整中值(Midline-estimating statistic of rhythm,MESOR)值高于正常对照组健康人,而振幅(Amplitude)小于正常对照组。结论血压近日节律的振幅降低是高血压病患者有别于健康人的特征。Objective To analyze the circadian rhythm of blood pressure, parameter characteristic of circadian rhythm in hypertensive subjects. Methods The cases of hypertensive group （n=59） and control group （n=74） were collected. Values of blood pressure were measured by Ambulatory Blood Pressure Monitoring every 30 min for 24 consecutive hours. After data of circadian rhythm in two groups had been analyzed by the cosine method, the parameters of circadian rhythm in two groups were compared by t test. Results Both control group and hypertensive group had circadian rhythm. Midline-estimating statistic of rhythm （MESOR） in hypertensive group was higher than that in control group. However, the amplitude of hypertensive group was lower than that of control group. Conclusion Compared with control group, hypertensive subjects have the characteristic of low amplitude.

关 键 词：近日节律 高血压病 振幅 特征 

分 类 号：R544.1[医药卫生—心血管疾病]