我国G9型轮状病毒VP7编码基因的序列分析  

SEQUENCE ANALYSIS OF THE GENE ENCODING VP7 OF A SEROTYPE 9 ROTAVIRUS FIELD STRAIN IDENTIFIED IN BEIJING

作　　者：李国华[1] 靖宇[1] 钱渊[1] 

机构地区：[1]首都儿科研究所北京市感染与免疫中心实验室

出　　处：《病毒学报》1997年第4期376-381,共6页Chinese Journal of Virology

摘　　要：我国Ｇ９型轮状病毒ＶＰ７编码基因的序列分析李国华靖宇钱渊（首都儿科研究所北京市感染与免疫中心实验室，北京１０００２０）关键词轮状病毒，ＶＰ７，序列分析Ａ组轮状病毒是导致婴幼儿重症腹泻的最重要病原，也是导致发展中国家婴幼儿死亡的主要原因之一〔１〕。轮状...In order to determine at the nucleotide level whether the strain T203 that was previously identified as rotavirus serotype 9 is distinct from established serotypes,the VP7 gene fragment from rotavirus strain T203 was cloned and sequenced.Comparative analysis of nucleotide sequence indicates that the strain T203 is distinguishable from serotypes 1-4 rotavirus(74%-78% homology)and similar to serotype 9 strains of WI61 and F45 (89% homology) at the nucleotide level.So the sequence analysis is consistent with previous report that designated T203 as rotavirus serotype 9.

关 键 词：轮状病毒 VP7 序列分析 编码基因 

分 类 号：R373.24[医药卫生—病原生物学]