滴通鼻炎水中黄芩苷含量的测定  

The Determination of the Baicalin in the Ditongbiyanshui

作　　者：李顺浓 

机构地区：[1]广东众生药业股份有限公司,广东东莞523325

出　　处：《今日药学》2008年第2期34-35,共2页Pharmacy Today

摘　　要：目的建立高效液相色谱法(HPLC法)测定滴通鼻炎水中黄芩苷含量的方法。方法采用C18250mm×4.6mm色谱柱,以甲醇-0.2%磷酸溶液(51∶49)为流动相,流速1.0ml/min,检测波长为280nm。结果黄芩苷进样量在8.4～42μg范围内,线性关系良好,r=0.9999;平均回收率为99.11%,RSD为1.5%。结论本法测定黄芩苷含量简便、快捷、准确,可用于该制剂的含量测定。Objective To establish a HPLC method for the determination of the baicalin in Ditong Biyanshui. Methods The Shimadzu C18 column （250 mm × 4.6 mm） was used, and the mobile phase was methanol-0.2% phosphoric acid （51 ： 49） with a flow rate at 1.0 ml/min, and the detection wavelength was 280 nm. Results The linear range of baicalin was 8.4 - 42 μg （r= 0.9999）; the average recovery was 99.11%; RSD was 1.5%. Conclusion The method is simple, accurate, reproducible, and can be used for the quality control of this preparation.

关 键 词：滴通鼻炎水 黄芩苷 高效液相色谱法 含量测定 

分 类 号：R284.2[医药卫生—中药学]