腔内置管溶栓治疗急性下肢深静脉血栓形成  

Thrombolysis Therapy by Cathetering in Treatment of Acute Deep Venous Thrombosis

作　　者：董富山[1] 曹会存[1] 姜喜锋[1] 王子亮[1] 李天晓[1] 

机构地区：[1]河南省人民医院放射科,郑州市450003

出　　处：《医药论坛杂志》2008年第8期31-32,35,共3页Journal of Medical Forum

摘　　要：目的探讨急性下肢深静脉血栓形成血管腔内置管溶栓的治疗方法及临床应用价值。方法对27例急性下肢深静脉血栓形成腔内置管溶栓治疗,其中男性18例,女性9例,年龄31～78岁,平均54岁,病程12h～8d。27例患者全部经彩超确诊为急性下肢深静脉血栓形成。所有患者先行下腔静脉和肾静脉DSA造影,再在下腔静脉内置入滤器,最后将溶栓导管直接插入病变血管,外接微量泵,持续注入尿激酶溶栓。结果27例患者中12例阻塞血管完全开通,15例部分开通,总有效率(患侧肢体疼痛和肿胀消失或明显减轻)100%,且无任何并发症发生。结论急性下肢深静脉血栓形成血管腔内置管溶栓疗效显著而且安全。Objective To evaluate the clinical efficacy of the cathetering thrombolysis therapy in the treatment of acute deep venous thrombosis of lower - limb. Methods Total 27patients with acute deep venous thrombosis were directly cathetered for thrombolytic therapy. There were 18 men and 9 women（ age range ,31 - 78 years ;mean,54 years ;history, 12h - 8d）. All patients were definitively diagnosed as acute deep venous thrombosis by uhrasonography. For each case, first DSA was performed for assess the inferior vena cava and the lower renal vein, then a filter was deployed into IVC, finally a catheter was inserted into the thrombotic segments. Catheterdirected Urokinase was continuely infused into the thrombotic segments. Results Complete resolution of thrombous occurred in 12 patients, and other 15 patients obtained partial resolution. All patients obtained effective fibrinolysis（ major/complete resolution of acute signs and symptoms）, and the total effective rate reached 100%. There were no episodes of any complications. Conclusion The thrombolytic therapy by cathetering is a safe and effective theraputic means in the treatment of acute deep venous thrombosis.

关 键 词：下肢深静脉血栓 置管 溶栓治疗 尿激酶 

分 类 号：R543.6[医药卫生—心血管疾病]