OX40L——冠心病新的炎症指标  

Ox40L:a New Inflammatory Index of Coronary Artery Disease

作　　者：林朴卿[1] 杨希立[2] 李键民[2] 

机构地区：[1]广东医学院,广东湛江524000 [2]佛山市第一人民医院心内科,广东佛山528000

出　　处：《医学综述》2008年第10期1457-1458,共2页Medical Recapitulate

摘　　要：冠心病为一种慢性炎症疾病。T细胞与动脉粥样斑块炎性反应关系密切。OX40/OX40L是机体炎性反应中一对重要的信号通路,参与T细胞的活化、增殖、迁移,在动脉粥样硬化的形成和发展中起到重要的作用。近来的研究表明,OX40/OX40L在冠心病的发生、发展中起重要作用,通过干预OX40/OX40L途径成为预防冠心病的一种新途径。Coronary artery disease is a kind of chronic inflammatory disease. T cell have a close relation-ship with inflammatory reaction in atheromatous plaque. OX40/OX4OL is a pair of important signaling in inflammatory reaction of the body,which took part in the activation,proliferation, migration of T cells,and played an important role in the genesis and development of atherosclerosis. Recent researches showed that OX40/OX40L played an important role in the genesis and development of coronary disease. It will be a new method to prevent coronary artery disease by interfering OX40/OX40L pathway.

关 键 词：冠心病 OX40/OX40L 炎症指标 

分 类 号：R541.4[医药卫生—心血管疾病]