胸部手术中的急性肺损伤研究现状  

Current Research Situation of Acute Lung Injury in Thoracic Surgical Procedures

作　　者：丁忠海[1] 许林[1] 

机构地区：[1]南京医科大学附属江苏省肿瘤医院胸外科,南京210009

出　　处：《医学综述》2008年第10期1494-1496,共3页Medical Recapitulate

基　　金：江苏省科技厅社会发展重点项目(BS2006005);江苏省卫生厅医学科研项目(k200405)

摘　　要：随着胸外科的发展,胸部手术中各种因素导致的急性肺损伤(ALI),已日益引起临床工作者的重视。术中肺缺血-再灌注损伤、肺组织的切除、术中麻醉药、输血、补液、通气方式等因素会导致ALI,而缩短阻断时间、缺血预处理、药物干预、术中注意等积极的预防能避免或减少ALI的发生。ALI的治疗包括机械通气、一氧化氮吸入、表面活性物质替代治疗、免疫治疗、药物治疗、血液净化、体外循环膜肺氧合及支气管肺泡灌洗等,文章就胸部手术中的ALI予以综述。With the development of the thoracic surgery, clinical scientists have paid more and more attention to the acute lung injury（ALI） caused by different factors in thoracic surgical procedures. In the operation , danger factors included lung ischemia reperfusion injury, resection of pulmonary tissue, narcotic, blood transfusion ,fluid replacement, ventilation method, energetic prevention such as shorten block time, ischemic preconditioning, drug intervention and caution in operation can avoid or reduce the ALl. The therapy included mechanical ventilation, nitric oxide inhalation, pulmonary surfacent substitution therapy, immunotherapy, drug treatment, blood purification, ertro corporeal membrane oxygenation and hronchoalveolar lavage. This article reviewed the ALI in thoracic surgical procedures.

关 键 词：胸部手术 急性肺损伤 研究现状 

分 类 号：R655.3[医药卫生—外科学] R563[医药卫生—临床医学]