健康成人儿童肾脏及心脏疾病患者的尿镁测定  

Clinical studies on the determination of urinary magneslum in healthy adults, children and patients with kidney or heart diseases

作　　者：贾贝克[1] 马会民[1] 宋明[1] 黄月仙[1] 梁树权[1] 

机构地区：[1]中国科学院化学研究所

出　　处：《微量元素与健康研究》1997年第4期13-14,共2页Studies of Trace Elements and Health

基　　金：国家自然科学基金;所长基金

摘　　要：对不同群体的尿镁同时进行测定与比较有助于更好地了解镁的临床意义。以新试剂聚２－丙烯胺缩－３－（４－甲酰基苯偶氮）－４，５－二羟基－２，７－萘二磺酸作显色剂，藉分光光度法同时测定了健康成年人、儿童肾脏及心脏病患者的尿镁。结果表明，健康人（包括儿童）的尿镁高于各种病人，其中与心脏病患者的差异无统计学意义，而与肾脏病患者却具有显著性统计学差异。提示尿镁浓度在一定程度上可反映肾脏的某些病变。To understand well the clinical significance of urinary magnesium,it is necessary to determine and compare simultaneously the urinary magnesium levels of different groups of people.In the present work,urinary magnesium concentrations in healthy adults,children and patients with kidney or heart diseases have been determined by spectrophotometry using a novel condensed product of polyallylamine and 3-(4-formylphenylazo)-4,5-dihydroxynaphthalene-2,7-disulfonic acid (PA-FPNS)as a highly selective polymeric chromogenic reagent.The results showed that urinary magnesium concentrations of healthy people including children are higher than that of various patients.The difference of urinary magnesium between healthy people and patients with heart diseases has no statistical significance,but that between healthy people and patients with kidney disases does have statistical importance,suggesting that urinary magnesium concentration may reflect to a certain extent some renal lesions.

关 键 词：尿液 镁 分光光度 肾疾病 心血管病 

分 类 号：R541.04[医药卫生—心血管疾病] R692.04[医药卫生—内科学]