药物致光敏性皮肤病  

Drug Induced Photosensitivity of Dermatosis

作　　者：严郁[1] 唐尧[1] 徐廷[1] 李天平[1] 

机构地区：[1]四川大学华西医院药剂科,四川成都610041

出　　处：《预防医学情报杂志》2008年第5期388-390,共3页Journal of Preventive Medicine Information

摘　　要：近年药物所致光敏性皮肤病发病率逐年升高,临床医生的重视程度也随之提升。光敏性皮炎可分成光毒性皮炎和光变态反应性皮炎。引起光敏反应的药物除常见喹诺酮类外,还包括四环素类、磺胺类、磺酰脲类、利尿药、吩噻嗪类、非甾体抗炎药、口服避孕药及局部用药等。可致光毒反应的药物有胺碘酮、喹诺酮类及四环素类药,而噻嗪类和苯佐卡因常可引起光变态反应。除药物外,还有一些物质会导致光敏性皮肤病。只有采取适当的防护措施,才能避免光敏反应的损害。In recent years, the incidence rate of drug induced photosensitivity dermatosis has increased annually; increasing concern has been put on it by clinicians. Photosensitivity-toxic dermatitis can be divided into phototoxic dermatitis and photoallergic dermatitis. The causes of photosensitive reactions, in addition to the common quinolone drugs, include tetracycline, sulfa, sulfonylurea, diuretics, phenothiazine, non-steroidal anti-inflammatory drugs, oral contraceptives, and local administration. Besides, there were some other substances which can lead to skin photosensitivity. Only by taking appropriate protective measures can we avoid the damage caused by photosensitive reaction.

关 键 词：药物 光敏性皮肤病 

分 类 号：R969.3[医药卫生—药理学] R758.14[医药卫生—药学]