均苯四甲酸酐酰化法测定10-羟基癸酸的研究  

Research on determining 10-hydroxydecanoic acid by acylation of PMDA

作　　者：高虹[1] 张国铭 曾伟明[1] 

机构地区：[1]广东轻工职业技术学院轻化工程系,广东广州510300 [2]广东理工职业技术学校,广东广州510500

出　　处：《化学工业与工程技术》2008年第2期1-3,共3页Journal of Chemical Industry & Engineering

基　　金：广东省科技计划项目(06B13801001)

摘　　要：研究了以吡啶为催化剂，利用均苯四甲酸酐（PMDA）与10-羟基癸酸分子中的醇羟基进行酰化反应来测定10一羟基癸酸的分析检验方法。实验表明，当样品0．12～0．18g，酰化反应时间20min、水解反应用水量5mL时，可准确测定10-羟基癸酸。并对不同的样品进行了加标回收试验，结果表明，回收率在101．2％～103．3％之间。An analytical method for the determination of 10 - hydroxydecanoic acid is researched. The method is based on the acylation reaction of PMDA with the hydroxyl in 10 -hydroxydecanoic acid, using pyridine as catalyst. The results showed that when the reaction time of acylation reaction is 20 min, and the water of hydrolysis reaction is 5 mL, the 10 - hydroxydecanoic acid can be determined precisely. The method has been applied to determine different samples of 10- hydroxydecanoic acid in beverage,and recoveries in the range of 101.2%-103.3% are obtained.

关 键 词：均苯四甲酸酐 10-羟基癸酸 酰化反应 

分 类 号：O623.6[理学—有机化学]