治疗心血管病药物的使用情况调查  

Investigation on the Cardiovascular drugs

作　　者：李兰茹[1] 王燕[1] 刘静[1] 

机构地区：[1]兰州军区总医院药材科,兰州730050

出　　处：《药学实践杂志》1997年第4期249-252,共4页Journal of Pharmaceutical Practice

摘　　要：本文随机抽取兰州军区总医院1994年1月至1995年12月出院病历44份，调查其中治疗心血管疾病的药物：抗心律失常药、β受体阻滞剂、钙拮抗剂、硝酸脂类、血管紧张素转化酶抑制剂（ACEI）等5类药的使用情况。根据WHO推荐的“限定日剂量（DDD）”的方法作为测量药物利用的单位，应用G～教授建议的药物利用指数（DUI）为指标对病历进行分析。结果表明：woo份病历中有166份使用上述5类药，约占41．5％。②所使用的5类心血管药物有14个品种，出现频率最高的有硝酸异山梨酯（56例次）、硝苯地平（53例次）、尼莫地平（50例次）、卡托普利（28例次）、普萘洛尔（21例次）、单硝酸异山梨酯（19例次）。③该5类心血管药物的使用与病人年龄相关。④1994年8种药物的DUI均≤1．0；1995年9种药物的DUI有7种均≤1．0，仅二种药稍＞1．0，提示无药物滥用情况，用药基本合理。The study was based on a survey of 400 randomly Selected Patients dischalged from the General Hospital of Lanzhou Military Command during January, 1994 to December, 1995.Five drugs were covered:anti - arrhythmic agents, β-adrenergic blocking agents, calcium channel blockers, nitrates, angiotensin converting enzyme inhibitors (ACEI). The methods of Definite Deily Dosage(DDD) recommended by WHO and Drug Utilization Index (DUI)by prof. Ghodse were employed. The results showed that: 1) the Cardiovascular drugs were used in 166 out of 400cases, accounting for 41. 5 %;2) the five classes involved 14 kinds of Cardiovascular drugs. A-mong the 14 kinds of drugs, the drugs frequently ed included isosorbide dinitrate(56),nifedipine(53),nimodipine(50),captopril(28),propranolol(21)and isosorbide mononitrate(19);3)the utilization of the 5 classes cardiovascular drugs was related to the ages of the the patients;4)the DUIof 8 in 1994 were less than 1.0; In 1995 the DUI of 7 were less than 1.0 and DUI of 2 kinds of drugs was basically rational.

关 键 词：心血管药物 限定日剂量 药物利用指数 

分 类 号：R972[医药卫生—药品]