新发现的内脏利什曼病流行区新疆民丰县Ⅰ．流行病学调查  

A Newly Identified Endemic Area of Visceral Leishmaniasis in Minfeng County of South Xinjiang Ⅰ. Epidemiological Survey

作　　者：伊斯拉音·乌斯曼[1] 金长发[2] 左新平[1] 顾灯安[2] 兰勤娴[2] 童苏祥[1] 李雄[1] 张仪[2] 茹孜古丽·朱马洪[1] 牛新玲[1] 阿不力米提 木合塔 阿布都外力 库尔班 

机构地区：[1]新疆维吾尔自治区疾病预防控制中心,乌鲁木齐830002 [2]中国疾病预防控制中心寄生虫病预防控制所,世界卫生组织疟疾、血吸虫病和丝虫病合作中心,上海200025 [3]新疆维吾尔自治区民丰县安迪尔乡卫生院,民丰848500 [4]新疆维吾尔自治区民丰县疾病预防控制中心,民丰848500

出　　处：《中国寄生虫学与寄生虫病杂志》2008年第2期128-131,共4页Chinese Journal of Parasitology and Parasitic Diseases

基　　金：科技部自然资源平台项目(No.2005DKA21104)~~

摘　　要：目的对新疆民丰县一个新发现的内脏利什曼病(黑热病)流行区进行现场流行病学调查。方法2007年6月采用回顾性调查和现况调查相结合,对民丰县安迪尔乡所有居民进行逐户入户调查。内容包括家庭成员中20年来的健康状况、既往有无疑似内脏利什曼病史(包括已过世者),并对15岁以下儿童进行体查(触诊肝、脾);对部分居民进行利什曼素皮内试验和rk39免疫层析试条检测。结果共调查居民313人,未见现症病例。既往有疑似内脏利什曼病史者60例,其中13例已过世。171人进行利什曼素皮内试验检测,阳性率为99.4%(170/171),其中有疑似内脏利什曼病病史者的阳性率为96.6%(28/29)。197人进行rk39免疫层析试条检测,阳性率为10.2%(20/197),其中有疑似内脏利什曼病史者的阳性率为19.4%(6/31),追溯诊断为既往内脏利什曼病病例。结论新疆民丰县为内脏利什曼病流行区。Objective To investigate the epidemiological status of visceral leishmaniasis in Minfeng county, a newly identified endemic area in south Xinjiang, China. Methods Based on a hint of possible existence of patients, a retrospective survey was carried out house by house in Andier Township of the county to find cases with suspected signs/symptoms of the disease in the past 20 years including those died. Meanwhile, a survey on current status was con- ducted, including physical examination（liver and spleen palpation） to those under 15 years-old, leishmanin skin test and rk39 immunochromatographic strip test for part of the residents. Results The investigation covered 313 local residents and revealed no case with present illness but 60 cases with a history of suspected signs/symptoms including 13 deaths, traced back as visceral leishmaniasis. Leishmanin skin test was performed in 171 people with a positive rate of 99.4% and 28 out of 29 suspected cases showed positive （96.6%）. rk39 immunochromatographic strip test was conducted in 197 people with a positive rate of 10.2% （20/197） and 19.4% （6/31） in those with a history of suspected signs/symptoms. Conclusion The epidemiological investigation indicates that the Andier Township of Minfeng County is an endemic area of visceral leishmaniasis.

关 键 词：内脏利什曼病(黑热病) 流行病学 rk39免疫层析试条 利什曼素皮内试验 新流行区 新疆 

分 类 号：R531.6[医药卫生—内科学]