^(99m)Tc-DTPA肾动态显像在先天性肾发育不良诊断中的临床应用  

Clinical application of ^(99m)Tc-DTPA renal dynamic imaging in the diagnosis of patients with congenital renal dysplasia

作　　者：李剑明[1] 李亚明[1] 

机构地区：[1]中国医科大学附属第一医院核医学科,辽宁沈阳110001

出　　处：《中国临床医学影像杂志》2008年第5期313-314,321,共3页Journal of China Clinic Medical Imaging

摘　　要：目的:探讨99mTc-二乙三氨五醋酸(DTPA)肾动态显像在先天性肾发育不良诊断中的临床应用价值。方法:12例先天性肾发育不良患者均行99mTc-DTPA肾动态显像和腹部超声检查,其中11例行腹部增强CT扫描,8例行静脉肾盂造影(IVP)。结果:99mTc-DTPA肾动态显像发现肾发育不良7例(58.3%,7/12),探测灵敏度与增强CT相当(χ2=1.5,P>0.05),优于B超(χ2=4.4,P<0.05);8例行IVP检查者仅发现肾发育不良2例。患侧肾小球滤过率(GFR)明显低于健侧(t=10.2,P<0.05)。结论:99mTc-DTPA肾动态显像是一种能有效诊断肾发育不良、并同时评价肾功能的无创性影像手段。Objective： To discuss the clinical application value of renal dynamic imaging in the diagnosis of patients with congenital renal dysplasia. Methods： Twelve cases with congenital renal dysplasia underwent ^99mTc-DTPA renal dynamic imaging and abdominal ultrasound examination, 11 cases among them underwent abdominal enhanced CT scan, and 8 cases among them underwent intravenous pyelography （IVP）. Results： Seven cases were diagnosed by ^99mTc-DTPA renal dynamic imaging （58.3%, 7/12）. The detection sensitivity by DTPA imaging was equivalent to enhanced CT scan（X^2=1.5, P〉0.05）, and was superior to ultrasound （X^2=4.4, P〈0.05）. Only 2 cases among 8 cases underwent IVP. The average values of GFR in the affected side kidney were obviously lower than normal side kidney（t=10.2, P〈0.05）. Conclusions： ^99mTc-DTPA renal dynamic imaging is an effective tool to diagnose renal dysplasia and evaluate kidney function at the same time.

关 键 词：肾疾病 放射性核素显像 

分 类 号：R692.12[医药卫生—泌尿科学] R817.4[医药卫生—外科学]