双参降血糖作用的研究  

Study on the Hypoglycenmic Effect of Triplostegia Glandulifera Wall

作　　者：刘晓波[1] 郭美仙[1] 李龙星[1] 赵旭[1] 王福生[1] 

机构地区：[1]大理学院药学院药理学教研室,云南大理671000

出　　处：《云南中医中药杂志》2008年第5期49-50,共2页Yunnan Journal of Traditional Chinese Medicine and Materia Medica

基　　金：云南省教育厅2004年资助项目(编号:04Y162c)

摘　　要：目的:研究双参的降血糖作用。方法:用10%葡萄糖及240μg/kg肾上腺素造成小鼠生理性高血糖模型,用80mg/kg四氧嘧啶造成小鼠糖尿病模型,观察双参对上述模型动物的血糖、体重、饮食量和饮水量的影响,从而观察双参的降血糖作用。结果:双参对正常小鼠无明显降低作用(P>0.05),但能降低葡萄糖及肾上腺素性高血糖小鼠的血糖水平(P<0.01,P<0.001),降低四氧嘧啶性糖尿病小鼠的血糖水平(P<0.05,P<0.01,P<0.001),减少动物的饮水量和饮食量。结论:双参对多种原因引起的高血糖均有一定的降糖作用。Objective:To study the hypoglycenmic effect of Triplostegia glandulifera Wall.Methods: A hyperlycosemia rat model was made by 10% of glucose and 240μg/kg of adrenaline and a diabetes rat model was made by 80mg/kg of alloxan to observe the effect of Triplostegia Glandulifera Wall on the blood sugar,weight,appetite for food and water of the test rats so as to know the hypoglycenmic effect of Triplostegia Glandulifera Wall.Results: Triplostegia glandulifera Wall showed no hypoglycenmic effect on healthy small rats(P>0.05),but reduced the blood sugar(P<0.01,P<0.001) of the glucose and adrenaline hyperlycosemia small rats and the blood sugar of the alloxan diabetes small rats and also reduced the appetite of the rats for food and water.Conclusion: Triplostegia glandulifera Wal has a certain hypoglycenmic effect on the treatment of hyperlycosemia induced by various factors.

关 键 词：双参 血糖 研究 

分 类 号：R285.5[医药卫生—中药学]