调脂安合剂提取工艺的研究  

Study on Extracting Process for Tiao ZhiAn Mixture

作　　者：张新广[1] 王冬梅[1] 黄虔[1] 

机构地区：[1]东莞市人民医院,广东东莞523018

出　　处：《中药材》2008年第4期594-597,共4页Journal of Chinese Medicinal Materials

摘　　要：目的:优选调脂安合剂最佳提取工艺。方法:采用单因素试验法,以挥发油得率为指标优选川芎、当归、姜黄药材的提取工艺;采用正交试验法以制何首乌中2,3,5,4′-四羟基二苯乙烯-2-O-β-D-葡萄糖苷的含量以及总固体得率为指标,综合评分优选群药的提取工艺。结果:川芎、当归、姜黄药材的最佳提取工艺为加水9倍量,提取8h;药渣与其余药材的优选提取工艺为加水6倍量,提取3次,每次1h。结论:优选的提取工艺提取率高,方法简便,适用于调脂安合剂的生产。Objective：To study the technology of optimal extraction for Tiao ZhiAn mixture. Methods： Optimization of the influence of the mixed volatile oil extracting of Ligusticum chuanxiong Hort. , Angelica sinensis（ Oliv. ）Diels and Curcuma longa L was chosen by single-index test. Orthogonal test was employed for selecting the optimum of extraction technology by colligation score as the indexes of the contents of stilbene glueoside of Polygunum multiflorum Thunb, total solid matters in water extraction. Results ： The best technology for extracting Ligusticum chuanxiong Hort. , Angelica sinensis （ oliv. ） Diels and Curcuma longa L was to add water nine times within eight hours. The way of adding water six times to the medicine sediment and other herbs, extracting 3 times in one hour each time was considered the optimum extraction technology. Conclusion： The considerable extraction rate of active components in the drugs is achieved by applying the selected technology, and the simple method is fit for manufacturing Tiao ZhiAn mixture.

关 键 词：调脂安合剂 单因素试验法 正交试验法 提取工艺 2 3 5 4’-四羟基二苯乙烯-2-O-β-D-葡萄糖苷 

分 类 号：R284.2[医药卫生—中药学]