动态脉压指数与冠脉狭窄程度的相关性研究  

Relationship between Ambulatory Pulse Pressure Indices and Severity of Coronary Artery Stenosis

作　　者：姬富才[1] 贾永平[1] 王凤群 吕吉元[1] 高宇平[1] 王睿[1] 范春雨[1] 

机构地区：[1]山西医科大学第一附属医院 [2]山西省太原钢铁公司总医院

出　　处：《中西医结合心脑血管病杂志》2008年第5期527-529,共3页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

基　　金：山西省教育厅高校科技研究开发基金项目(No.20041011)

摘　　要：目的探讨动态各脉压指数（PPI）与冠脉病变狭窄程度的关系。方法对156例入选病例均行冠脉造影术,其中男103例,女53例,年龄33岁-81岁（59.15岁±10.60岁）。所有病例均于术后监测24 h动态血压,并计算各病例24 h PPI、白昼PPI及夜间PPI。冠脉病变的狭窄程度用病变的血管支数及Gensini积分表示。结果冠脉狭窄组24 h动态血压监测,无论24 h、白昼还是夜间,其收缩压（SBP）、脉压（PP）及PPI均显著高于冠脉正常组（P〈0.05）,且SBP、PP及PPI均随冠脉血管狭窄支数的增加而逐渐增加。多因素Logistic回归分析结果显示：动态各PPI均与冠心病（CHD）冠脉狭窄程度的关系最为密切;且夜间PPI较其他因素与CHD冠脉狭窄程度的关系更密切。结论动态各PPI均是CHD冠脉狭窄发生发展的独立危险因素,且夜间PPI的预测价值更佳。Objective To assess the relationship between ambulatory pulse pressure indices （PPI） and the severity of coronary artery stenosis. Methods One hundred and fifty - six patients （pts） were included. All pts underwent coronary angiography. Ambulatory blood pressure was measured after coronary angiography. The severity of coronary artery stenosis was evaluated by the number of impaired arteries and Gensini score. Results Systolic blood pressure, pulse pressure and PPI in pts with coronary heart disease （CHD） in twenty- four hour, day and night were all significantly higher than that in normal subjects. Logistic multivariate analysis indicated that different ambulatory PPI were all closely related to the severity of coronary artery stenosis. And the night PPI was the best predictor for the severity of coronary artery stenosis. Conclusion Ambulatory PPI was an independent risk factors of the severity of coronary artery stenosis,and the night PPI was the best predictor of severity of CHD.

关 键 词：脉压指数 冠脉造影术 冠脉狭窄 

分 类 号：R543[医药卫生—心血管疾病]