巴斯德毕赤酵母表达系统在动物传染病防制中应用的研究进展  

Advance in application of Pichia pastoris expression system in the control of animal infectious diseases

作　　者：孙静[1] 孙惠玲[2] 张培君[2] 

机构地区：[1]首都师范大学生命科学学院,北京100037 [2]北京市农林科学院畜牧兽医研究所,北京100094

出　　处：《中国兽医科学》2008年第5期451-455,共5页Chinese Veterinary Science

基　　金：北京市科技新星计划项目(2006B42)

摘　　要：从表达载体、宿主细胞、培养条件3个方面概述了巴斯德毕赤酵母表达系统的特点,综述了其在抗菌肽生产、动物疫苗生产以及动物疾病诊断试剂盒研制中应用的最新进展,展望了巴斯德毕赤酵母表达系统在动物传染病研究中的应用前景。The characteristics of Pichia pastoris expression system were summarized from the aspects of expression vectors, host strains and cultivation conditions. The recent applications of P. pastoris expres- sion system in the production of antimicrobial peptides and vaccines,and the development of diagnostic kits for animal diseases were reviewed. Finally,prospect of the P. pastoris expression system in studies of animal infectious diseases was discussed.

关 键 词：巴斯德毕赤酵母 动物传染病 表达 应用 

分 类 号：S855[农业科学—临床兽医学]