肿节风浸膏中的总黄酮和香豆素部位的谱图指纹差异研究  

Fingerprint differences between total flavonoids and coumarins of Sarcandra glabra extract

作　　者：倪小兰 徐国良[2] 肖兵华[3] 付玉梅 张启云[2] 陈奇[3] 

机构地区：[1]江中药业股份有限公司,江西南昌330096 [2]江西中医学院现代中药制剂教育部重点实验室,江西南昌330004 [3]江西中医学院,江西南昌330004

出　　处：《中成药》2008年第5期628-631,共4页Chinese Traditional Patent Medicine

基　　金：国家自然科学基金资助项目(No.30260122);江西省自然基金资助项目(0640161)

摘　　要：目的:比较大孔吸附树脂分离的肿节风浸膏中的总黄酮部位和香豆素部位的谱图指纹差异。方法:采用指纹图谱技术,建立了肿节风浸膏的指纹图谱。结果:总黄酮部位与香豆素部位的特征指纹的峰数量和峰面积有差异。结论:大孔吸附树脂能较好地分离药物的药效部位,谱图指纹能较好地表征药效部位。AIM： To compare the fingerprints difference between total flavonoids and coumarins of Sarcandra glabra extract separated by macroporous adsorption resin. METHODS： To establish HPLC fingerprint chromatogram of Sarcandra glabra extract and to evaluate the constituents. RESULTS： The difference fingerprint was showed in total flavonoid part and coumarin part. CONCLUSION： Drug action part could be separated by macroporous adsorption resin and exosyndromed by Spectrogram fingerprints.

关 键 词：肿节风 总黄酮 香豆素 指纹图谱 

分 类 号：R284.1[医药卫生—中药学]